Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LITAF | Q99732 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.41 |
| ▸ | PLD2 | O14939 | 2/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512471 | 1.00 | DAO (0.53) | DAOHSD11B1DRD2DRD4DRD3 | |
| SCHEMBL29198145 | 0.89 | DAO (0.52) | DAOHSD11B1DRD2DRD4DRD3 | |
| SCHEMBL29198148 | 0.89 | DAO (0.52) | DAOHSD11B1DRD2DRD4DRD3 | |
| SCHEMBL30870521 | 0.87 | HSD11B1 (0.43) | DAOHSD11B1DRD2DRD4DRD3 | |
| SCHEMBL28506788 | 0.83 | OPRM1 (0.59) | HSD11B1DRD2OPRM1TNKSTNKS2 | |
| SCHEMBL28506786 | 0.83 | OPRM1 (0.59) | HSD11B1DRD2OPRM1TNKSTNKS2 | |
| SCHEMBL5388279 | 0.83 | DAO (0.55) | DAOHSD11B1DRD2DRD4DRD3 | |
| SCHEMBL22869414 | 0.82 | MTNR1A (0.52) | DAOHSD11B1 | |
| SCHEMBL28500852 | 0.81 | CHRM1 (0.55) | DAOHSD11B1DRD2OPRM1TNKS | |
| SCHEMBL28505104 | 0.81 | OPRM1 (0.45) | HSD11B1DRD2OPRM1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |
| CN-112074511-A | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2020-12-11 | — | — | CN | disclosed |