Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 7/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343399 | 0.78 | L3MBTL1 (0.44) | L3MBTL1CCR2ALDH1A1EPAS1TSHR | |
| SCHEMBL31453874 | 0.78 | L3MBTL1 (0.44) | L3MBTL1CCR2ALDH1A1EPAS1TSHR | |
| SCHEMBL9712600 | 0.75 | ALDH1A1 (0.43) | TDP1ALDH1A1TSHRCYP2C19CYP1A2 | |
| SCHEMBL6015172 | 0.75 | TDP1 (0.45) | L3MBTL1TDP1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL9448525 | 0.74 | CCR2 (0.40) | L3MBTL1CCR2ALDH1A1EPAS1HSD11B1 | |
| SCHEMBL27440247 | 0.74 | L3MBTL1 (0.37) | L3MBTL1CCR2ALDH1A1EPAS1TSHR | |
| SCHEMBL2600014 | 0.73 | TDP1 (0.53) | CCR2TDP1ALDH1A1 | |
| SCHEMBL29954698 | 0.72 | TDP1 (0.42) | TDP1ALDH1A1TSHRCYP2C19CYP1A2 | |
| SCHEMBL20742678 | 0.72 | TDP1 (0.38) | TDP1ALDH1A1TSHRCYP2C19CYP1A2 | |
| SCHEMBL21121085 | 0.72 | TDP1 (0.42) | TDP1ALDH1A1TSHRCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-A | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2021-01-15 | — | — | CN | disclosed |