Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512403 | 0.87 | TRPA1 (0.56) | GPR84TRPA1CSNK2A1AHRCYP2A6 | |
| SCHEMBL28505468 | 0.82 | CSNK2A1 (0.45) | GPR84TRPA1CSNK2A1AHRSLC6A2 | |
| SCHEMBL28511617 | 0.81 | AHR (0.46) | GPR84TRPA1CSNK2A1AHRCYP2A6 | |
| SCHEMBL13548692 | 0.76 | AHR (0.51) | GPR84TRPA1AHRHTR1ASLC6A2 | |
| SCHEMBL916587 | 0.73 | GPR84 (0.69) | GPR84TRPA1CSNK2A1AHRCYP2A6 | |
| SCHEMBL29507011 | 0.73 | GPR84 (0.69) | GPR84TRPA1CSNK2A1AHRCYP2A6 | |
| SCHEMBL2304604 | 0.73 | TLR8 (0.58) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL20084712 | 0.72 | CSNK2A1 (0.46) | GPR84CSNK2A1AHRCYP2A6NR4A2 | |
| SCHEMBL18593225 | 0.71 | SMN1; SMN2 (0.44) | CSNK2A1RHEBSLC6A4 | |
| SCHEMBL20536057 | 0.70 | TRPA1 (0.74) | TRPA1AHRHTR1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300154-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112300154-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-02-02 | — | — | CN | disclosed |