Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606133 | 0.84 | RORC (0.67) | RORC | |
| SCHEMBL21606068 | 0.83 | RORC (0.64) | RORC | |
| SCHEMBL21605491 | 0.81 | RORC (0.55) | RORC | |
| SCHEMBL29724936 | 0.81 | RORC (0.55) | RORC | |
| SCHEMBL21605651 | 0.81 | FAAH (0.41) | RORC | |
| SCHEMBL21606096 | 0.79 | RORC (0.69) | RORC | |
| SCHEMBL28507687 | 0.77 | RORC (0.67) | RORC | |
| SCHEMBL21606203 | 0.77 | FAAH (0.41) | — | |
| SCHEMBL21607426 | 0.75 | FAAH (0.41) | — | |
| SCHEMBL21606097 | 0.74 | RORC (0.62) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292183-A | 6-aminopyridin-3-yl-pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |