Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21605491 | 1.00 | RORC (0.55) | RORC | |
| SCHEMBL28910635 | 0.90 | RORC (0.53) | RORC | |
| SCHEMBL23478209 | 0.84 | RORC (0.68) | RORC | |
| SCHEMBL21605651 | 0.82 | FAAH (0.41) | RORC | |
| SCHEMBL21605594 | 0.82 | RORC (0.68) | RORC | |
| SCHEMBL28513613 | 0.81 | RORC (0.53) | RORC | |
| SCHEMBL21605607 | 0.79 | RORC (0.66) | RORC | |
| SCHEMBL21605508 | 0.78 | RORC (0.69) | RORC | |
| SCHEMBL21605529 | 0.77 | RORC (0.66) | RORC | |
| SCHEMBL21606203 | 0.77 | FAAH (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807261-B1 | PYRIDINYL PYRAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2022-07-13 | — | — | EP | disclosed |