Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506071 | 0.84 | RAB9A (0.64) | ALDH1A1KMT2AHSD17B10SMN1; SMN2GAA | |
| SCHEMBL8188037 | 0.80 | ALDH1A1 (0.77) | ALDH1A1PKMKMT2AMAPTMEN1 | |
| SCHEMBL16208771 | 0.80 | ALDH1A1 (0.74) | ALDH1A1PKMKMT2AMAPTMEN1 | |
| SCHEMBL24210088 | 0.79 | KMT2A (0.83) | ALDH1A1PKMKMT2AMAPTMEN1 | |
| SCHEMBL6722194 | 0.79 | MAPT (0.75) | ALDH1A1PKMKMT2AMAPTMEN1 | |
| SCHEMBL24209779 | 0.79 | KMT2A (0.76) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL1702530 | 0.79 | CYP1A2 (0.92) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL24029044 | 0.76 | ALDH1A1 (0.67) | ALDH1A1PKMKMT2AMAPTMEN1 | |
| SCHEMBL24210195 | 0.76 | KMT2A (0.73) | ALDH1A1KMT2AMEN1KDM4EUSP2 | |
| SCHEMBL24209778 | 0.76 | NPSR1 (0.67) | ALDH1A1PKMKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028833-A | Para-aminosalicylic acid azole derivative and preparation method and application thereof | 西南大学 | 2020-12-04 | — | — | CN | disclosed |