Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889493 | 0.87 | HDAC4 (0.42) | DAOGSK3BALDH1A1KDM4ENPSR1 | |
| SCHEMBL5889494 | 0.81 | DAO (0.50) | DAOKMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL5290034 | 0.81 | DAO (0.50) | DAOKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL70702 | 0.76 | DAO (0.63) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL7651777 | 0.75 | CES2 (0.64) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL5889507 | 0.74 | NPSR1 (0.41) | KMT2AALDH1A1KDM4ENPSR1PPARG | |
| SCHEMBL5966698 | 0.74 | RAB9A (0.53) | KMT2AALDH1A1KDM4EPPARGNCOA1 | |
| SCHEMBL31250450 | 0.74 | KMT2A (0.55) | CES2CES1DAOKMT2AALDH1A1 | |
| SCHEMBL64687 | 0.71 | HDAC3 (0.58) | CES2CES1DAOGSK3BKMT2A | |
| SCHEMBL5043396 | 0.71 | CES2 (0.53) | CES2CES1DAOGSK3BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028875-B | Anhydride compounds of PGI2 protein agonist and TXA2 protein inhibitor | 南昌弘益科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-112028875-A | Anhydride compounds of PGI2 protein agonist and TXA2 protein inhibitor | 南昌弘益科技有限公司 | 2020-12-04 | — | — | CN | disclosed |