Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PHGDH | O43175 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28171807 | 0.86 | HSD11B1 (0.63) | MGLLHSD11B1KMT2AMEN1POLB | |
| SCHEMBL28504433 | 0.82 | POLB (0.66) | MGLLHSD11B1KMT2APOLBALDH1A1 | |
| SCHEMBL1805653 | 0.82 | PARP10 (0.58) | MGLLMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1806630 | 0.82 | HRH3 (0.64) | MGLLMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28422447 | 0.81 | HTT (0.47) | MGLLMAPTHSD11B1KMT2AMEN1 | |
| SCHEMBL28171808 | 0.81 | EPHX2 (0.54) | HSD11B1ALDH1A1 | |
| SCHEMBL647507 | 0.81 | MGLL (0.69) | MGLLMAPTHSD11B1KMT2AMEN1 | |
| SCHEMBL12188726 | 0.80 | MGLL (0.67) | MGLLMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28510717 | 0.80 | MEN1 (0.49) | MAPTKMT2AMEN1HSD17B10GLA | |
| SCHEMBL28753553 | 0.80 | MGLL (0.52) | MGLLMAPTHSD11B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226808-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |