Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.58 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20661175 | 1.00 | TRPV1 (0.58) | TRPV1GPR52ESR1CYP3A4KDM4E | |
| Platyphyllenone SCHEMBL15013533 | 0.84 | GPR52 (0.72) | TRPV1GPR52ESR1CYP3A4KDM4E | |
| Platyphyllenone SCHEMBL15379838 | 0.84 | GPR52 (0.72) | TRPV1GPR52ESR1CYP3A4KDM4E | |
| SCHEMBL3341890 | 0.84 | GPR52 (0.72) | TRPV1GPR52ALDH1A1GAAMAPT | |
| SCHEMBL3341887 | 0.84 | GPR52 (0.72) | TRPV1GPR52ALDH1A1GAAMAPT | |
| SCHEMBL13311223 | 0.82 | TRPV1 (0.73) | TRPV1GPR52ESR1CYP3A4KDM4E | |
| SCHEMBL15275172 | 0.81 | HTR1A (0.51) | TRPV1GPR52ESR1CYP3A4CYP1A2 | |
| SCHEMBL6373438 | 0.79 | GPR52 (0.84) | TRPV1GPR52CYP19A1ALOX5 | |
| SCHEMBL11938332 | 0.79 | HTR1A (0.49) | TRPV1GPR52CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL12414343 | 0.77 | LTA4H (0.75) | TRPV1CYP3A4ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111973576-A | Curcumin nano dispersion film and preparation method and application thereof | 苏州泉硕纳米科技有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-111973576-A | Curcumin nano dispersion film and preparation method and application thereof | 苏州泉硕纳米科技有限公司 | 2020-11-24 | — | — | CN | disclosed |