Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520239 | 0.76 | FAAH (0.35) | — | |
| SCHEMBL28186915 | 0.73 | — | — | |
| SCHEMBL28249299 | 0.69 | MAPK1 (0.33) | NOS3NOS1MAPK1HTT | |
| SCHEMBL18016332 | 0.60 | GUSB (0.32) | — | |
| SCHEMBL4403128 | 0.55 | MAPK1 (0.41) | NOS3NOS1MAPK1HTT | |
| SCHEMBL4103553 | 0.53 | ALDH1A1 (0.36) | NOS3NOS1MAPK1HTT | |
| SCHEMBL18805368 | 0.52 | ALDH1A1 (0.55) | NOS3NOS1HTT | |
| SCHEMBL2204413 | 0.52 | ALDH1A1 (0.55) | NOS3NOS1HTT | |
| SCHEMBL50033 | 0.51 | ALDH1A1 (0.45) | NOS3NOS1MAPK1HTT | |
| SCHEMBL50026 | 0.51 | ALDH1A1 (0.39) | NOS3NOS1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727422-B | Six-membered nitrogen oxygen silicon heterocyclic compound and preparation method thereof | 中国石油天然气股份有限公司 | 2021-01-01 | — | — | CN | disclosed |