Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805368 | 1.00 | ALDH1A1 (0.55) | ALDH1A1IDO1LRRK2TTRMIF | |
| SCHEMBL14806769 | 0.84 | ALDH1A1 (0.79) | ALDH1A1IDO1LRRK2TTRSMN1; SMN2 | |
| SCHEMBL9510943 | 0.82 | ALDH1A1 (0.84) | ALDH1A1IDO1LRRK2TTRSMN1; SMN2 | |
| SCHEMBL4402316 | 0.78 | ALDH1A1 (0.42) | ALDH1A1IDO1LRRK2TTRSMN1; SMN2 | |
| SCHEMBL4726618 | 0.74 | ALDH1A1 (0.62) | ALDH1A1IDO1LRRK2TTRSMN1; SMN2 | |
| SCHEMBL34461896 | 0.74 | ALDH1A1 (0.62) | ALDH1A1IDO1LRRK2TTRSMN1; SMN2 | |
| SCHEMBL31282241 | 0.74 | ALDH1A1 (0.54) | ALDH1A1IDO1LRRK2TTRSMN1; SMN2 | |
| SCHEMBL755432 | 0.73 | ALDH1A1 (0.47) | ALDH1A1IDO1LRRK2MIFHTR3E | |
| SCHEMBL14252204 | 0.72 | ALDH1A1 (0.54) | ALDH1A1IDO1LRRK2TTRMAPT | |
| SCHEMBL18786507 | 0.71 | ALDH1A1 (0.45) | ALDH1A1IDO1LRRK2MIFHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11342504-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | NOVALED GMBH (DE) | 2022-05-24 | — | — | US | disclosed |
| US-20200152873-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | NOVALED GMBH (DE) | 2020-05-14 | — | — | US | disclosed |
| US-10586926-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | NOVALED GMBH (DE) | 2020-03-10 | — | — | US | disclosed |
| US-20180076389-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | NOVALED GMBH (DE) | 2018-03-15 | — | — | US | disclosed |
| US-9876172-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | NOVALED GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-20150097146-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | NOVALED GMBH (DE) | 2015-04-09 | — | — | US | disclosed |
| US-8911645-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | NOVALED AG (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20140070145-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | NOVALED AG (DE) | 2014-03-13 | — | — | US | disclosed |
| US-8617426-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | NOVALED AG (DE) | 2013-12-31 | — | — | US | disclosed |
| US-20110309309-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | NOVALED AG (DE) | 2011-12-22 | — | — | US | disclosed |
| US-7981324-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | NOVALED AG (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20080265216-A1 | Use as doping agent for doping organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, electronic component; 1,3-Bi(dicyanomethylene)indane-2-ylidene-bis(4-oxo-[3,5-di-t-butyl]-2,5-cyclohexadienylidene)cyclopropane | NOVALED AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180076389-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | DNMT3B, CHRNB1, CHRNB2 | ALDH1A1 4459/4885IDO1 1327/4885LRRK2 4152/4885 |
| US-20200152873-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | DNMT3B, CHRNB1, CHRNB2 | ALDH1A1 4459/4885IDO1 1327/4885LRRK2 4152/4885 |
| US-10586926-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | DNMT3B, CHRNB1, CHRNB2 | ALDH1A1 4459/4885IDO1 1327/4885LRRK2 4152/4885 |
| US-11342504-B2 | Oxocarbon-, pseudooxocarbon- and radialene compounds and their use | DNMT3B, CHRNB1, CHRNB2 | ALDH1A1 4459/4885IDO1 1327/4885LRRK2 4152/4885 |
| US-20110309309-A1 | Oxocarbon-, Pseudooxocarbon- and Radialene Compounds and Their Use | DNMT3B, CHRNB1, CHRNB2 | ALDH1A1 4459/4885IDO1 1327/4885LRRK2 4152/4885 |
| US-20080265216-A1 | Use as doping agent for doping organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, electronic component; 1,3-Bi(dicyanomethylene)indane-2-ylidene-bis(4-oxo-[3,5-di-t-butyl]-2,5-cyclohexadienylidene)cyclopropane | CHRNB1, GJB2, CHRNB3 | ALDH1A1 3361/4885IDO1 276/4885LRRK2 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.