Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 7/20 | 0.36 |
| ▸ | PER2 | O15055 | 3/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847036 | 0.89 | PER2 (0.35) | SRCPER2TNKSTNKS2 | |
| SCHEMBL2302485 | 0.87 | CHKA (0.43) | SRCALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL2855217 | 0.85 | TNKS (0.43) | SRCTNKSTNKS2 | |
| SCHEMBL2301601 | 0.82 | PDE4D (0.39) | SRCPER2CNR2PDE4APDE4B | |
| SCHEMBL2299396 | 0.79 | TNKS (0.36) | PER2TNKSTNKS2CNR1PDE4A | |
| SCHEMBL12386309 | 0.79 | PER2 (0.36) | SRCPER2CNR2 | |
| SCHEMBL2301464 | 0.78 | HRH3 (0.49) | CNR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2303903 | 0.77 | PKM (0.45) | — | |
| SCHEMBL13513407 | 0.76 | HRH3 (0.41) | CNR2ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL2299174 | 0.76 | PER2 (0.40) | PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021337-B1 | INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2010-01-13 | — | — | EP | claimed |