Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 8/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302093 | 0.87 | TNKS (0.44) | TNKSTNKS2 | |
| SCHEMBL2851534 | 0.85 | SLC6A3 (0.37) | TNKSTNKS2SRC | |
| SCHEMBL2297696 | 0.82 | TNKS (0.41) | TNKSTNKS2 | |
| SCHEMBL2302521 | 0.81 | KCNH2 (0.47) | — | |
| SCHEMBL12386310 | 0.79 | TNKS (0.38) | TNKSTNKS2 | |
| SCHEMBL13513555 | 0.76 | L3MBTL3 (0.39) | TNKSTNKS2 | |
| SCHEMBL12386299 | 0.76 | TNKS (0.42) | TNKSTNKS2 | |
| SCHEMBL2296894 | 0.75 | NAMPT (0.41) | TNKSTNKS2 | |
| SCHEMBL2301150 | 0.75 | NAMPT (0.41) | TNKSTNKS2 | |
| SCHEMBL2299298 | 0.75 | NAMPT (0.41) | TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021337-B1 | INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2010-01-13 | — | — | EP | claimed |