Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 9/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bumetrizole SCHEMBL8164248 | 0.90 | NPC1 (0.40) | GSK3BOXER1RBP4VCAM1 | |
| SCHEMBL28559946 | 0.85 | SCN5A (0.36) | NR5A2NR5A1GSK3BOXER1CNR1 | |
| SCHEMBL29241 | 0.84 | NPC1 (0.41) | — | |
| SCHEMBL29349567 | 0.84 | NPC1 (0.41) | — | |
| SCHEMBL8741026 | 0.82 | CNR1 (0.38) | CNR1CNR2 | |
| Propionic Acid SCHEMBL6295773 | 0.82 | OXER1 (0.36) | OXER1CNR1CNR2 | |
| SCHEMBL23908723 | 0.82 | NPC1 (0.38) | NR5A2NR5A1 | |
| SCHEMBL9879793 | 0.81 | VCAM1 (0.36) | VCAM1CNR1CNR2 | |
| SCHEMBL2187685 | 0.81 | CYP1A2 (0.38) | GSK3BCNR1CNR2 | |
| SCHEMBL28646965 | 0.81 | VCAM1 (0.38) | GSK3BVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721972-B | PET reflective film with high reflectivity | 银金达(上海)新材料有限公司 | 2021-01-22 | — | — | CN | disclosed |