Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227613 | 0.98 | TRPV4 (0.58) | TRPV4DEGS1PIK3CAPI4KBPIK3CD | |
| SCHEMBL29918406 | 0.98 | TRPV4 (0.58) | TRPV4DEGS1PIK3CAPI4KBPIK3CD | |
| SCHEMBL25212518 | 0.83 | TRPV4 (0.44) | TRPV4PIK3CAPI4KBMAP4K4KCNH2 | |
| SCHEMBL322603 | 0.81 | KIF11 (0.52) | TRPV4PIK3CAPI4KBPIK3CDPIK3CB | |
| SCHEMBL30536021 | 0.81 | KIF11 (0.52) | TRPV4PIK3CAPI4KBPIK3CDPIK3CB | |
| SCHEMBL21327619 | 0.78 | MRGPRX4 (0.40) | TRPV4MRGPRX4DAO | |
| SCHEMBL1511379 | 0.77 | TRPV4 (0.36) | TRPV4DEGS1 | |
| SCHEMBL21377437 | 0.76 | CSF1R (0.53) | DEGS1HDAC4KCNH2 | |
| SCHEMBL1474089 | 0.74 | LMNA (0.42) | DEGS1CYP2C9 | |
| SCHEMBL29484952 | 0.74 | LMNA (0.42) | DEGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530396-A | Modified acrylic emulsion and application thereof | 中山市新谷新材料有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-117088878-A | High-activity Wnt pathway inhibitor compound | 杭州阿诺生物医药科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-117088876-A | High-activity Wnt pathway inhibitor compound | 杭州阿诺生物医药科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-118530396-A | Modified acrylic emulsion and application thereof | 中山市新谷新材料有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117088878-A | High-activity Wnt pathway inhibitor compound | 杭州阿诺生物医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117088876-A | High-activity Wnt pathway inhibitor compound | 杭州阿诺生物医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112194616-A | Microwave synthesis method of 6-trifluoromethyl pyridine formaldehyde | 复旦大学 | 2021-01-08 | — | — | CN | disclosed |