Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522076 | 0.81 | TDP1 (0.38) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL14881615 | 0.75 | PLAT (0.53) | ALDH1A1KDM4EMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL28514550 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10HPGDHCRTR1 | |
| SCHEMBL23013790 | 0.73 | PLAT (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL15307002 | 0.73 | KMT2A (0.46) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL24833959 | 0.71 | PLAT (0.41) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL24274526 | 0.70 | ADORA3 (0.46) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL404918 | 0.70 | PLAT (0.53) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL541988 | 0.69 | NPC1 (0.54) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL3268718 | 0.69 | CA12 (0.54) | ALDH1A1KDM4EHSD17B10HPGDHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003161-B | Neurotrophic factor tyrosine kinase receptor inhibitors | 正大天晴药业集团股份有限公司 | 2020-10-09 | — | — | CN | disclosed |