Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14881615 | 0.84 | PLAT (0.53) | PLATKDM4EALDH1A1ATMHTT | |
| SCHEMBL15307002 | 0.81 | KMT2A (0.46) | PLATKDM4EALDH1A1ATMHTT | |
| SCHEMBL23013790 | 0.81 | PLAT (0.43) | PLATKDM4EALDH1A1ATMHTT | |
| SCHEMBL22018907 | 0.75 | PLAT (0.44) | PLATPOLBKDM4EALDH1A1ATM | |
| SCHEMBL404918 | 0.71 | PLAT (0.53) | PLATKDM4EALDH1A1GLAHPGD | |
| SCHEMBL28516116 | 0.71 | ALDH1A1 (0.49) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24274526 | 0.69 | ADORA3 (0.46) | PLATPOLBKDM4EALDH1A1ADORA3 | |
| SCHEMBL17820828 | 0.68 | PLAT (0.36) | PLATKMT2ANPC1RAB9A | |
| SCHEMBL24533108 | 0.67 | TSHR (0.46) | PLATPOLBKDM4EALDH1A1ATM | |
| SCHEMBL14881835 | 0.66 | MAPT (0.42) | PLATPOLBKDM4EALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002410-A1 | COMPOUND AS HIGHLY SELECTIVE ROS1 INHIBITOR AND USE THEREOF | GUANGZHOU JOYO PHARMATECH CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002410-A1 | COMPOUND AS HIGHLY SELECTIVE ROS1 INHIBITOR AND USE THEREOF | ROS1, NOX1, NOX4 | PLAT 4087/4885POLB 3255/4885KDM4E 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.