Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 9/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617972 | 0.92 | LPL (0.43) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL587344 | 0.80 | LPL (0.39) | LPLLIPGROCK1 | |
| SCHEMBL23134738 | 0.79 | LPL (0.36) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL14488670 | 0.79 | LIPG (0.38) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL29016499 | 0.77 | LPL (0.47) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL21141913 | 0.76 | ESR1 (0.32) | — | |
| SCHEMBL4219113 | 0.76 | LPL (0.38) | LPLLIPGROCK1 | |
| SCHEMBL14488668 | 0.76 | ROCK1 (0.39) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL23124209 | 0.76 | LPL (0.43) | LPLLIPGROCK1CA1CA2 | |
| SCHEMBL21311963 | 0.74 | LPL (0.44) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334455-B | C-mannoside compounds for the treatment of urinary tract infections | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-112334455-A | C-mannoside compounds for the treatment of urinary tract infections | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-05 | — | — | CN | disclosed |