Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587211 | 0.92 | LPL (0.44) | LPLLIPGROCK1F2F11 | |
| SCHEMBL28906593 | 0.81 | LPL (0.39) | LPLLIPGROCK1F2F11 | |
| SCHEMBL28516240 | 0.80 | LPL (0.38) | LPLLIPGROCK1 | |
| SCHEMBL2393633 | 0.80 | LPL (0.36) | LPLLIPGROCK1F2F11 | |
| SCHEMBL31256428 | 0.78 | LPL (0.36) | LPLLIPGF2F11PRSS1 | |
| SCHEMBL29016499 | 0.78 | LPL (0.47) | LPLLIPGROCK1F11 | |
| SCHEMBL16532616 | 0.78 | LPL (0.38) | LPLLIPGF2F11PRSS1 | |
| SCHEMBL24616359 | 0.77 | LPL (0.35) | LPLLIPGF2F11PRSS1 | |
| SCHEMBL14488668 | 0.77 | ROCK1 (0.39) | LPLLIPGROCK1F11FFAR1 | |
| SCHEMBL14488670 | 0.77 | LIPG (0.38) | LPLLIPGROCK1F11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417131-A1 | ISOXAZOL-3(2H)-ONE ANALOGS AS THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117323-A1 | METHOD AND APPARATUS FOR PRODUCING HEAT ENERGY AND CARBON DIOXIDE | ASTRAZENECA AB (SE) | 2010-10-14 | — | — | WO | disclosed |