Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Oleamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28502738 | 1.00 | FAAH (0.62) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL28927356 | 0.99 | FAAH (0.64) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL1958103 | 0.92 | SOAT1 (0.46) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4660135 | 0.90 | SOAT1 (0.47) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL4624710 | 0.83 | FAAH (0.74) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL28412088 | 0.83 | FAAH (0.74) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL28132793 | 0.81 | FAAH (0.77) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL21051941 | 0.81 | FAAH (0.96) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL28132794 | 0.80 | FAAH (0.74) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL4365854 | 0.79 | FAAH (0.79) | FAAHSOAT1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112226225-A | Temperature-resistant and salt-resistant surfactant composition for pressure reduction and injection increase of water injection well of low-permeability oil reservoir and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-01-15 | — | — | CN | disclosed |