Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660135 | 0.98 | SOAT1 (0.47) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL28502738 | 0.92 | FAAH (0.62) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Oleamide SCHEMBL28516627 | 0.92 | FAAH (0.62) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Oleamide SCHEMBL28927356 | 0.90 | FAAH (0.64) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Palmitamide SCHEMBL28980258 | 0.85 | SOAT1 (0.47) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Palmitamide SCHEMBL27825196 | 0.85 | SOAT1 (0.50) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL1705678 | 0.79 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Octadecanoic Acid Amide SCHEMBL5346586 | 0.79 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL28807747 | 0.79 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Palmitamide SCHEMBL3831146 | 0.79 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099955-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | HTL BIOTECHNOLOGY INNOVATION INC. | 2024-03-28 | — | — | US | disclosed |
| EP-4288084-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | Modern Meadow, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-3398585-B1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | HAYASHIBARA CO (JP) | 2020-02-26 | — | — | EP | disclosed |
| US-20190008747-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3398585-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-10111822-B2 | External dermal composition for anti-ageing and method for producing the same | Hayashibara Co., Ltd. (JP) | 2018-10-30 | — | — | US | disclosed |
| EP-2939657-B1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | HAYASHIBARA CO (JP) | 2018-08-08 | — | — | EP | disclosed |
| EP-2516510-B1 | SURFACE-TREATMENT AGENT FOR POWDER FOR USE IN COSMETIC AND COSMETIC CONTAINING POWDER TREATED WITH THE SAME | DOW CORNING TORAY CO LTD (JP) | 2017-01-25 | — | — | EP | disclosed |
| EP-2515841-B1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME | DOW CORNING TORAY CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| US-9260607-B2 | Surface-treatment agent for powder for use in cosmetic and cosmetic containing powder treated with the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9221952-B2 | Linear and cyclic siloxanes and cosmetic compositions made thereof | DOW CORNING TORAY CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-20150342854-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-2939657-A1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | Hayashibara Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-20120263662-A1 | Copolymer Having Carbosiloxane Dendrimer Structure, And Composition And Cosmetic Containing The Same | DOW TORAY CO., LTD. (JP) | 2012-10-18 | — | — | US | disclosed |
| EP-2507248-A1 | LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF | Dow Corning Toray Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20120251605-A1 | Surface-Treatment Agent For Powder For Use In Cosmetic And Cosmetic Containing Powder Treated With The Same | DOW TORAY CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120237583-A1 | Linear And Cyclic Siloxanes And Cosmetic Compositions Made Thereof | DOW TORAY CO., LTD. (JP) | 2012-09-20 | — | — | US | disclosed |
| WO-2011068250-A1 | LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263662-A1 | Copolymer Having Carbosiloxane Dendrimer Structure, And Composition And Cosmetic Containing The Same | TAS2R8, CUTA, TAS2R43 | SOAT1 4315/4885MEN1 2663/4885FAAH 4526/4885 |
| US-20120237583-A1 | Linear And Cyclic Siloxanes And Cosmetic Compositions Made Thereof | TAS2R8, TAS2R5, TAS2R7 | SOAT1 4606/4885MEN1 656/4885FAAH 3841/4885 |
| US-20120251605-A1 | Surface-Treatment Agent For Powder For Use In Cosmetic And Cosmetic Containing Powder Treated With The Same | CUTA, GPKOW, TAS2R8 | SOAT1 3059/4885MEN1 3148/4885FAAH 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.