Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057549 | 1.00 | NAAA (0.48) | NAAAASAH1EPHX1NAMPTKDM4E | |
| SCHEMBL7557165 | 1.00 | NAAA (0.48) | NAAAASAH1EPHX1NAMPTKDM4E | |
| SCHEMBL30880341 | 0.98 | NAAA (0.45) | NAAAASAH1EPHX1NAMPTKDM4E | |
| SCHEMBL4256419 | 0.94 | QPCT (0.43) | NAAAASAH1EPHX1MAPK1HTT | |
| SCHEMBL7553681 | 0.92 | EPHX2 (0.47) | — | |
| SCHEMBL22494115 | 0.92 | EPHX2 (0.47) | — | |
| SCHEMBL5257422 | 0.87 | QPCT (0.45) | NAMPTMAPK1SMN1; SMN2 | |
| SCHEMBL15212788 | 0.85 | TSHR (0.39) | KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL10421135 | 0.84 | PAOX (0.43) | — | |
| SCHEMBL20531021 | 0.83 | GAA (0.36) | ASAH1MAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| EP-1915063-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | Quest International Services B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007013811-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-02-01 | — | — | WO | disclosed |
| EP-1222916-A2 | Use of amino-alcohol derivatives containing a urea function as moisturiser in cosmetic or dermatological compositions | L'OREAL (FR) | 2002-07-17 | — | — | EP | disclosed |
| EP-0815829-B1 | Use of amino-alcohol derivatives containing an urea function in cosmetic and dermatologic compositions | OREAL (FR) | 2002-07-03 | — | — | EP | disclosed |
| US-6335024-B2 | MOISTURIZER FOR SKIN AND HAIR | L'OREAL (FR) | 2002-01-01 | — | — | US | disclosed |
| US-20010007675-A1 | Cosmetic and dermatological compositions containing aminoalchohol derivatives containing a urea functional group and uses thereof | L'OREAL | 2001-07-12 | — | — | US | disclosed |
| US-6093412-A | MOISTURIZING THE SKIN OR CONDITIONING THE HAIR | L'OREAL (FR) | 2000-07-25 | — | — | US | disclosed |
| US-6010707-A | MOISTURIZING AGENT | L'OREAL (FR) | 2000-01-04 | — | — | US | disclosed |
| EP-0815829-A1 | Use of amino-alcohol derivatives containing an urea function in cosmetic and dermatologic compositions | L'OREAL (FR) | 1998-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007675-A1 | Cosmetic and dermatological compositions containing aminoalchohol derivatives containing a urea functional group and uses thereof | HRH3, BCAT1, CUTA | NAAA 690/4885ASAH1 183/4885EPHX1 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.