Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599850 | 1.00 | ATM (0.37) | ATMTHRBPARP1PARP15PARP10 | |
| SCHEMBL3649807 | 1.00 | ATM (0.37) | ATMTHRBPARP1PARP15PARP10 | |
| SCHEMBL29090337 | 0.88 | THRB (0.41) | ATMTHRBPARP10 | |
| SCHEMBL9957309 | 0.88 | THRB (0.41) | ATMTHRBPARP10 | |
| SCHEMBL3712187 | 0.87 | ATM (0.39) | ATM | |
| SCHEMBL28407513 | 0.86 | THRB (0.37) | ATMTHRBPARP10 | |
| SCHEMBL17374176 | 0.82 | — | — | |
| SCHEMBL28453661 | 0.80 | ESR2 (0.36) | ATMTHRBPARP10 | |
| SCHEMBL5985695 | 0.79 | TDP1 (0.40) | THRB | |
| SCHEMBL11547378 | 0.79 | TDP1 (0.40) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117015528-A | Indole derivatives as kinase inhibitors | GB005股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |