Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957309 | 1.00 | THRB (0.41) | THRBATMMAPTCYP3A4CYP2C9 | |
| SCHEMBL28407513 | 0.94 | THRB (0.37) | THRBATMMAPTCYP3A4CYP2C9 | |
| SCHEMBL3649807 | 0.88 | ATM (0.37) | THRBATMPARP10 | |
| SCHEMBL28516952 | 0.88 | ATM (0.37) | THRBATMPARP10 | |
| SCHEMBL28599850 | 0.88 | ATM (0.37) | THRBATMPARP10 | |
| SCHEMBL28453661 | 0.85 | ESR2 (0.36) | THRBATMPDE4APDE4BPDE4C | |
| SCHEMBL8805010 | 0.81 | THRB (0.45) | THRBMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19996621 | 0.81 | THRB (0.45) | THRBMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28062771 | 0.79 | ATM (0.34) | ATMPARP10 | |
| SCHEMBL17374176 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015528-A | Indole derivatives as kinase inhibitors | GB005股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116891460-A | Indazole derivative or pharmaceutically acceptable salt thereof and application thereof | 浙江大学 | 2023-10-17 | — | — | CN | disclosed |