Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514744 | 0.88 | HTR7 (0.41) | ENPP3ENPP1CYP11B1CYP11B2HPGD | |
| SCHEMBL28510819 | 0.81 | RAB9A (0.46) | CYP11B1CYP11B2HPGDALDH1A1RAB9A | |
| SCHEMBL28504247 | 0.79 | NPC1 (0.51) | CYP11B1CYP11B2HPGDALDH1A1RAB9A | |
| SCHEMBL28506806 | 0.79 | NPC1 (0.51) | CYP11B1CYP11B2HPGDALDH1A1RAB9A | |
| SCHEMBL28502050 | 0.77 | RAB9A (0.45) | ENPP3CYP11B1CYP11B2HPGDALDH1A1 | |
| SCHEMBL28501588 | 0.75 | NPC1 (0.51) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28906122 | 0.75 | NPC1 (0.51) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28506057 | 0.75 | RAB9A (0.46) | CYP11B1CYP11B2HPGDALDH1A1RAB9A | |
| SCHEMBL28557865 | 0.75 | MEN1 (0.41) | CYP11B1CYP11B2HPGDALDH1A1RAB9A | |
| SCHEMBL12600997 | 0.75 | CYP11B1 (0.47) | CYP11B1CYP11B2HPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159364-B | Synthetic method of isothiazole derivative | 温州大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-112159364-A | Synthetic method of isothiazole derivative | 温州大学 | 2021-01-01 | — | — | CN | disclosed |