Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516987 | 0.88 | ENPP3 (0.43) | HTR7ALDH1A1NPC1HPGDTSHR | |
| SCHEMBL28510819 | 0.79 | RAB9A (0.46) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28504247 | 0.77 | NPC1 (0.51) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28506806 | 0.77 | NPC1 (0.51) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28506057 | 0.77 | RAB9A (0.46) | ALDH1A1NPC1HPGDTSHRRAB9A | |
| SCHEMBL28502050 | 0.76 | RAB9A (0.45) | ALDH1A1NPC1HPGDTSHRRAB9A | |
| SCHEMBL31603858 | 0.75 | CYP1A2 (0.41) | HTR7ALDH1A1NPC1HPGDTSHR | |
| SCHEMBL8113541 | 0.74 | ADRA1A (0.38) | ALDH1A1NPC1HPGDTSHRRAB9A | |
| SCHEMBL12731313 | 0.71 | CYP19A1 (0.47) | ALDH1A1NPC1HPGDTSHRRAB9A | |
| SCHEMBL13490261 | 0.71 | RAB9A (0.64) | ALDH1A1NPC1HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159364-B | Synthetic method of isothiazole derivative | 温州大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-112159364-A | Synthetic method of isothiazole derivative | 温州大学 | 2021-01-01 | — | — | CN | disclosed |