Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.54 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439141 | 0.88 | AGTR1 (0.53) | AGTR1AGTR2GP6 | |
| SCHEMBL359 | 0.85 | GP6 (0.63) | AGTR1AGTR2GP6 | |
| SCHEMBL28517096 | 0.82 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL8791631 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2GP6 | |
| SCHEMBL8791309 | 0.82 | AGTR1 (0.60) | AGTR1AGTR2GP6 | |
| SCHEMBL3324054 | 0.82 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL8792485 | 0.81 | AGTR1 (0.64) | AGTR1AGTR2GP6 | |
| SCHEMBL28517015 | 0.81 | AGTR1 (0.54) | AGTR1AGTR2GP6 | |
| SCHEMBL4544027 | 0.80 | NPBWR1 (0.42) | — | |
| SCHEMBL8719876 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084028-A2 | IMPROVED PROCESS FOR MANUFACTURING ANHYDROUS (E)-3-[2-BUTYL-1- {(4-CARBOXYPHENYL) METHYL}-1H-IMIDAZOLE-5-YL]-(THIOPHEN-2- YLMETHYL)PROP-2-ENOIC ACID METHANE SULFONATE | NEULAND LABORATORIES LTD (IN) | 2009-07-09 | — | — | WO | disclosed |
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5728842-A | ANGIOTENSIN II RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1993006828-A1 | MEDICAMENT FOR THE TREATMENT OF ANXIETY | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-15 | — | — | WO | disclosed |