Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | CDC42 | P60953 | 1/20 | 0.31 |
| ▸ | RAC1 | P63000 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591714 | 0.77 | KMT2A (0.36) | MEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL21591673 | 0.77 | KMT2A (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL23706004 | 0.76 | KMT2A (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL2943288 | 0.76 | MLYCD (0.36) | MEN1KMT2ATDP1 | |
| SCHEMBL9935388 | 0.76 | KMT2A (0.40) | MEN1KMT2ATDP1TSHR | |
| SCHEMBL28514936 | 0.75 | PTGS2 (0.35) | AKR1C3AKR1C2MEN1KMT2ATDP1 | |
| SCHEMBL21591695 | 0.73 | MEN1 (0.37) | MEN1KMT2ATDP1 | |
| SCHEMBL29009931 | 0.71 | PTGS2 (0.34) | AKR1C3AKR1C2MEN1KMT2APTGS2 | |
| SCHEMBL17732184 | 0.71 | MAPT (0.34) | MEN1KMT2ATDP1 | |
| SCHEMBL21591708 | 0.69 | OPRK1 (0.37) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313228-A | Novel heteroaryl heterocyclyl compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2021-02-02 | — | — | CN | disclosed |