Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KIF5B | P33176 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514423 | 0.83 | LMNA (0.39) | TRPA1LMNARAB9AMEN1KMT2A | |
| SCHEMBL21858763 | 0.82 | TRPA1 (0.50) | TRPA1LMNARAB9AMEN1KMT2A | |
| SCHEMBL21611401 | 0.77 | LMNA (0.53) | LMNARAB9AMEN1KMT2APOLB | |
| SCHEMBL21611480 | 0.77 | SMN1; SMN2 (0.56) | LMNARAB9AMEN1KMT2AMAPT | |
| SCHEMBL28523656 | 0.77 | MAPT (0.47) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL21611512 | 0.75 | MAP4K4 (0.48) | TRPA1LMNAKMT2AFLT3 | |
| SCHEMBL21611499 | 0.75 | LMNA (0.56) | LMNAMRGPRX1MAPTRETKDR | |
| SCHEMBL21611513 | 0.73 | EGFR (0.60) | LMNAMEN1KMT2AMAPTRET | |
| SCHEMBL21611408 | 0.73 | MRGPRX1 (0.52) | TRPA1LMNAMEN1KMT2AMRGPRX1 | |
| SCHEMBL21611421 | 0.73 | EGFR (0.60) | LMNAMEN1KMT2AMAPTRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368276-A | Amino-pyrimidinone derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-02-12 | — | — | CN | disclosed |