SCHEMBL28517482

SCHEMBL28517482

Cc1ccc(C2=C[CH]c3ccccc32)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.39
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
NPC1 O15118 2/20 0.36
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 4/20 0.33
HTT P42858 2/20 0.33
NOTUM Q6P988 1/20 0.33
MAPT P10636 3/20 0.33
MAPK1 P28482 2/20 0.33
MCOLN3 Q8TDD5 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PTGS2 P35354 1/20 0.31
TSHR P16473 1/20 0.31
ACHE P22303 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025947 0.84 ACHE (0.35) MEN1KMT2ALMNAL3MBTL1GAA
SCHEMBL28515419 0.81 NPC1 (0.39) MEN1KMT2ANPC1LMNAL3MBTL1
SCHEMBL28512208 0.79 RAB9A (0.39) MEN1KMT2ANPC1LMNAL3MBTL1
SCHEMBL28025423 0.78 BRD9 (0.34) MEN1KMT2ANPC1LMNAMAPT
SCHEMBL28025999 0.78 MEN1 (0.33) MEN1KMT2ALMNAALDH1A1HTT
SCHEMBL28821513 0.76 GSTP1 (0.46) ALDH1A1SMN1; SMN2NPSR1TSHR
SCHEMBL28302278 0.76 BRD9 (0.33) LMNAMAPTTSHRACHE
SCHEMBL28512609 0.75 ELANE (0.40) MEN1KMT2ANPC1LMNAL3MBTL1
SCHEMBL28025430 0.75 MAOB (0.39) ALDH1A1NOTUMMAPTMAPK1RAB9A
SCHEMBL28025954 0.75 GSTP1 (0.40) ALDH1A1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed