Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20549513 | 0.70 | NPC1 (0.31) | CDK1MAPKAPK2NPC1RAB9ALMNA | |
| SCHEMBL20549515 | 0.70 | NPC1 (0.31) | CDK1MAPKAPK2NPC1RAB9ALMNA | |
| SCHEMBL8090872 | 0.70 | ADRA2A (0.47) | MEN1KMT2AKDM4EALOX15HSD17B10 | |
| SCHEMBL15508249 | 0.68 | NPC1 (0.31) | CDK1MAPKAPK2NPC1RAB9ACYP1A2 | |
| SCHEMBL16928520 | 0.68 | NPC1 (0.31) | CDK1MAPKAPK2NPC1RAB9ACYP1A2 | |
| SCHEMBL30570963 | 0.68 | NPC1 (0.31) | CDK1MAPKAPK2NPC1RAB9ACYP1A2 | |
| SCHEMBL29004249 | 0.68 | NPC1 (0.31) | CDK1MAPKAPK2NPC1RAB9ACYP1A2 | |
| SCHEMBL29898372 | 0.68 | NPC1 (0.31) | CDK1MAPKAPK2NPC1RAB9ACYP1A2 | |
| SCHEMBL30570974 | 0.68 | CYP1A2 (0.38) | KMT2AHSD17B10HTR2AHTR2CHTR2B | |
| SCHEMBL29070741 | 0.68 | CYP1A2 (0.38) | KMT2AHSD17B10HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112266364-B | Preparation method of tetrahydroquinoxaline compound | 云南民族大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-112266364-A | Preparation method of tetrahydroquinoxaline compound | 云南民族大学 | 2021-01-26 | — | — | CN | disclosed |