Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.68 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | CTSD | P07339 | 6/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.55 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518104 | 1.00 | PSMB5 (0.68) | PSMB5FAAHCTSDRENKISS1R | |
| SCHEMBL28525513 | 0.89 | PSMB5 (0.63) | PSMB5FAAHCTSDKISS1RCTSB | |
| SCHEMBL28525512 | 0.89 | PSMB5 (0.63) | PSMB5FAAHCTSDKISS1RCTSB | |
| SCHEMBL4392116 | 0.88 | FAAH (0.70) | PSMB5FAAH | |
| SCHEMBL4392110 | 0.88 | FAAH (0.70) | PSMB5FAAH | |
| SCHEMBL3672145 | 0.87 | PLA2G2A (0.56) | PSMB5FAAHCTSDREN | |
| SCHEMBL3672141 | 0.87 | PLA2G2A (0.56) | PSMB5FAAHCTSDREN | |
| SCHEMBL28517814 | 0.86 | CTSD (0.53) | PSMB5FAAHCTSDRENKISS1R | |
| SCHEMBL28560400 | 0.86 | CTSD (0.53) | PSMB5FAAHCTSDRENKISS1R | |
| SCHEMBL29535660 | 0.86 | CTSD (0.53) | PSMB5FAAHCTSDRENKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279887-A | Amino acid derivative, preparation method and application thereof, anti-tumor micelle and preparation method thereof | 首都医科大学 | 2021-01-29 | — | — | CN | claimed |
| CN-112279887-A | Amino acid derivative, preparation method and application thereof, anti-tumor micelle and preparation method thereof | 首都医科大学 | 2021-01-29 | — | — | CN | disclosed |
| CN-112279887-A | Amino acid derivative, preparation method and application thereof, anti-tumor micelle and preparation method thereof | 首都医科大学 | 2021-01-29 | — | — | CN | disclosed |