SCHEMBL2851865

SCHEMBL2851865

CCCP(CCC)c1ccccc1Nc1ccccc1P(CCC)CCC

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16318152 0.88 CYP3A4 (0.34)
SCHEMBL946616 0.83 KMT2A (0.33) MAPK1MAPTHTT
SCHEMBL15656314 0.82 TP53 (0.33)
SCHEMBL15658789 0.76 MAP2K7 (0.31) MAPT
SCHEMBL7563978 0.74 ACHE (0.39) MAPTHTT
SCHEMBL4608738 0.73 LMNA (0.33) MAPK1
SCHEMBL17529691 0.73 CA1 (0.46) MAPK1MAPTHTT
SCHEMBL2958764 0.72
SCHEMBL27476668 0.72 CYP1A2 (0.38) MAPT
SCHEMBL6947163 0.72 MAPT (0.45) MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436111-B2 Nickel catalyst system for the preparation of high CIS polybutadiene BRIDGESTONE CORPORATION (JP) 2013-05-07 US claimed
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US claimed
US-8436111-B2 Nickel catalyst system for the preparation of high CIS polybutadiene BRIDGESTONE CORPORATION (JP) 2013-05-07 US disclosed
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US disclosed