SCHEMBL946616

SCHEMBL946616

CCP(CC)c1ccccc1Nc1ccccc1P(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.32
HTT P42858 1/20 0.32
POLB P06746 2/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 2/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PSIP1 O75475 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
CDC25B P30305 1/20 0.30
CLCN2 P51788 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6947163 0.88 MAPT (0.45) KMT2AMAPTNPC1RAB9ALMNA
SCHEMBL2851865 0.83 MAPK1 (0.31) MAPTHTTMAPK1
SCHEMBL2912079 0.80 TP53 (0.36) HTTTP53PSIP1ALDH1A1GAA
SCHEMBL30616094 0.80 TP53 (0.36) HTTTP53PSIP1ALDH1A1GAA
SCHEMBL4608738 0.77 LMNA (0.33) KMT2APOLBLMNATP53MAPK1
SCHEMBL10960827 0.74 SMN1; SMN2 (0.61) KMT2AHTTPOLBNPC1RAB9A
SCHEMBL24469059 0.74
SCHEMBL2851891 0.73 MAPT (0.31) KMT2AMAPTHTTPOLBLMNA
SCHEMBL4449690 0.73 TP53 (0.32) MAPTNPC1RAB9ALMNATP53
SCHEMBL16318152 0.73 CYP3A4 (0.34) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436111-B2 Nickel catalyst system for the preparation of high CIS polybutadiene BRIDGESTONE CORPORATION (JP) 2013-05-07 US claimed
EP-1456153-B1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST SASOL TECH PTY LTD (ZA) 2012-06-13 EP claimed
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US claimed
US-7361623-B2 Trimerisation and oligomerisation of olefins using a chromium based catalyst SASOL TECHNOLOGY (PTY) LTD. (ZA) 2008-04-22 US claimed
US-20050119516-A1 Trimerization of ethylene with a catalyst system comprising a coordination catalyst of a chromium source complexed with a di(alkylphosphinoalkyl)amino ligand, and an alumoxane; improved catalyst selectivity SASOL TECHNOLOGY (PTY) LTD. (ZA) 2005-06-02 US claimed
EP-2287144-B1 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL CO LP (US) 2018-04-11 EP disclosed
EP-2287143-B1 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL CO LP (US) 2018-04-11 EP disclosed
US-20170044275-A9 Methods of Preparation of an Olefin Oligomerization Catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-02-16 US disclosed
US-9550841-B2 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-01-24 US disclosed
US-20160251455-A1 Methods of Preparation of an Olefin Oligomerization Catalyst CHEVRON PHILLIPS CHEMICAL CO LP (US) 2016-09-01 US disclosed
EP-1716089-B1 METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL CO (US) 2015-04-08 EP disclosed
US-8993822-B2 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-03-31 US disclosed
US-20070043181-A1 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP 2007-02-22 US disclosed
EP-1716089-A1 METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST Chevron Phillips Chemical Company LP (US) 2006-11-02 EP disclosed
WO-2005082816-A1 METHODS OF PREPARATION OF AN OLEFIN OLIGOMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2005-09-09 WO disclosed
US-20050187391-A1 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-08-25 US disclosed
US-20050187098-A1 Methods of preparation of an olefin oligomerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2005-08-25 US disclosed
US-20050119516-A1 Trimerization of ethylene with a catalyst system comprising a coordination catalyst of a chromium source complexed with a di(alkylphosphinoalkyl)amino ligand, and an alumoxane; improved catalyst selectivity SASOL TECHNOLOGY (PTY) LTD. (ZA) 2005-06-02 US disclosed
EP-1456153-A1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST Sasol Technology (Pty) Ltd (ZA) 2004-09-15 EP disclosed
WO-2003053891-A1 TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST SASOL TECHNOLOGY (PTY) LTD. (ZA) 2003-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050187391-A1 Methods of preparation of an olefin oligomerization catalyst ZRANB2, COG4, PPOX KMT2A 3314/4885MAPT 1142/4885HTT 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.