Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524107 | 0.92 | RAB9A (0.53) | GAALMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL28908703 | 0.87 | ALDH1A1 (0.55) | GAALMNAMEN1KMT2ANPSR1 | |
| SCHEMBL28522245 | 0.85 | CA12 (0.53) | GAALMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL28525496 | 0.85 | ALDH1A1 (0.49) | GAALMNAMEN1KMT2AHTT | |
| SCHEMBL28529501 | 0.85 | ALDH1A1 (0.60) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL2485289 | 0.85 | KMT2A (0.50) | GAALMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL2485286 | 0.85 | KMT2A (0.50) | GAALMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL2482095 | 0.85 | ALDH1A1 (0.56) | GAALMNAMEN1KMT2AHTT | |
| SCHEMBL28528129 | 0.85 | PDE2A (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL28987216 | 0.82 | LMNA (0.56) | GAALMNAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279743-B | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-112279743-A | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2021-01-29 | — | — | CN | disclosed |