Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23854654 | 0.82 | MAPK1 (0.59) | RAB9ANPC1NR1I2AHRSMN1; SMN2 | |
| SCHEMBL13678342 | 0.81 | RAB9A (0.47) | HCAR3HCAR2RAB9ANPC1NR1I2 | |
| SCHEMBL16534093 | 0.77 | HCAR3 (0.49) | HCAR3HCAR2DYRK1AALPLTP53 | |
| SCHEMBL15318182 | 0.77 | RAB9A (0.53) | RAB9ANPC1NR1I2AHRSMN1; SMN2 | |
| SCHEMBL3498417 | 0.77 | CCNA2 (0.60) | HCAR2RAB9ANPC1NR1I2AHR | |
| SCHEMBL4420465 | 0.77 | RAB9A (0.57) | RAB9ANPC1NR1I2AHRSMN1; SMN2 | |
| SCHEMBL15318183 | 0.76 | RAB9A (0.51) | RAB9ANPC1NR1I2AHRSMN1; SMN2 | |
| SCHEMBL15318181 | 0.76 | RAB9A (0.51) | RAB9ANPC1NR1I2AHRSMN1; SMN2 | |
| SCHEMBL14397160 | 0.75 | HCAR3 (0.47) | HCAR3HCAR2RAB9ANPC1ALPL | |
| SCHEMBL11001220 | 0.73 | MAPK14 (0.53) | RAB9ANPC1NR1I2AHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334462-A | OGA inhibitor compounds | 詹森药业有限公司 | 2021-02-05 | — | — | CN | disclosed |