SCHEMBL28518684

SCHEMBL28518684

Nc1cccc(-c2nnn[nH]2)c1.[Ni]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.53
HPGD P15428 4/20 0.45
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 3/20 0.45
TP53 P04637 3/20 0.45
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ATAD2 Q6PL18 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PRMT1 Q99873 1/20 0.44
MAOA P21397 1/20 0.44
PDPK1 O15530 1/20 0.42
AURKA O14965 1/20 0.42
MECP2 P51608 1/20 0.42
MAP4K4 O95819 4/20 0.42
METAP2 P50579 1/20 0.41
MAPT P10636 2/20 0.41
PKM P14618 2/20 0.41
GFER P55789 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581828 0.98 ENPP2 (0.54) ENPP2HPGDKDM4EALDH1A1NPC1
SCHEMBL266617 0.98 ENPP2 (0.54) ENPP2HPGDKDM4EALDH1A1NPC1
SCHEMBL28515571 0.96 ENPP2 (0.53) ENPP2HPGDKDM4EALDH1A1NPC1
Hydrochloric Acid SCHEMBL27945737 0.96 ENPP2 (0.53) ENPP2HPGDKDM4EALDH1A1NPC1
Hydrochloric Acid SCHEMBL6177189 0.96 ENPP2 (0.53) ENPP2HPGDKDM4EALDH1A1NPC1
SCHEMBL28523028 0.96 ENPP2 (0.53) ENPP2HPGDKDM4EALDH1A1NPC1
SCHEMBL12761250 0.85 GP6 (0.37) ENPP2HPGDKDM4EALDH1A1NPC1
SCHEMBL8258334 0.82 AURKA (0.58) ENPP2PDPK1AURKAMAP4K4AXL
SCHEMBL6160731 0.79 USP2 (0.34) ENPP2HPGDALDH1A1SMN1; SMN2HSD17B10
Hydrochloric Acid SCHEMBL4640912 0.78 ALDH1A1 (0.37) ENPP2HPGDKDM4EALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111747993-A Porous nickel complex, preparation method thereof and application thereof in catalysis 旌德君创科技发展有限公司 2020-10-09 CN disclosed