SCHEMBL28519082

SCHEMBL28519082

NC(=O)Oc1cccc(C[C@H](N)CO)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
TAAR1 Q96RJ0 2/20 0.44
ANPEP P15144 1/20 0.42
ENPEP Q07075 1/20 0.42
ACHE P22303 5/20 0.40
EPHX1 P07099 1/20 0.39
PCNA P12004 1/20 0.39
LIG1 P18858 1/20 0.39
NOS3 P29474 2/20 0.38
NOS1 P29475 2/20 0.38
NOS2 P35228 2/20 0.38
SLC7A5 Q01650 2/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
ALPI P09923 1/20 0.38
PKM P14618 1/20 0.38
PTGS1 P23219 1/20 0.38
XIAP P98170 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28519083 1.00 MEN1 (0.56) MEN1KMT2ATAAR1ANPEPENPEP
SCHEMBL2723540 0.80 KMT2A (0.68) MEN1KMT2AACHENOS3NOS1
SCHEMBL28524607 0.80 ACHE (0.41) TAAR1ANPEPENPEPACHESLC7A5
SCHEMBL28101915 0.80 ACHE (0.41) TAAR1ANPEPENPEPACHESLC7A5
SCHEMBL28244500 0.80 TAAR1 (0.70) TAAR1
SCHEMBL29337151 0.80 TAAR1 (0.70) TAAR1
SCHEMBL5230197 0.78 EPHX1 (0.50) TAAR1EPHX1PCNALIG1PPARG
Hydrochloric Acid SCHEMBL11695113 0.78 TAAR1 (0.68) TAAR1
SCHEMBL27526614 0.77 KMT2A (0.68) MEN1KMT2AACHENOS3NOS1
SCHEMBL3827847 0.77 KMT2A (0.53) MEN1KMT2ATAAR1ACHEPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116615252-A anti-CD 48 antibodies, antibody drug conjugates and uses thereof 诺华股份有限公司 2023-08-18 CN disclosed
CN-112437675-A Antibody drug conjugates for ablating hematopoietic stem cells 诺华股份有限公司 2021-03-02 CN disclosed