Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.48 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.48 |
| ▸ | PCNA | P12004 | 1/20 | 0.47 |
| ▸ | LIG1 | P18858 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379287 | 0.86 | LTA4H (0.60) | EPHX1PPARGPPARASCN9APCNA | |
| SCHEMBL12379282 | 0.86 | LTA4H (0.60) | EPHX1PPARGPPARASCN9APCNA | |
| Hydrochloric Acid SCHEMBL2287546 | 0.85 | LTA4H (0.58) | EPHX1PPARGPPARASCN9APCNA | |
| Hydrochloric Acid SCHEMBL6479299 | 0.85 | LTA4H (0.58) | EPHX1PPARGPPARASCN9APCNA | |
| Hydrochloric Acid SCHEMBL6479293 | 0.85 | LTA4H (0.58) | EPHX1PPARGPPARASCN9APCNA | |
| Hydrochloric Acid SCHEMBL2296279 | 0.85 | LTA4H (0.58) | EPHX1PPARGPPARASCN9APCNA | |
| Hydrochloric Acid SCHEMBL2287540 | 0.85 | LTA4H (0.58) | EPHX1PPARGPPARASCN9APCNA | |
| SCHEMBL5225775 | 0.83 | FDFT1 (0.46) | EPHX1PPARGPPARASCN9AFDFT1 | |
| L-Phenylalaninol SCHEMBL8174775 | 0.83 | PPARG (0.54) | EPHX1PPARGPPARASCN9APCNA | |
| SCHEMBL30942602 | 0.82 | ALDH1A1 (0.56) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092435-B1 | REMEDIES FOR DIABETES | KYOWA HAKKO KOGYO KK (JP) | 2007-04-04 | — | — | EP | disclosed |
| US-6489331-B1 | A CONDENSED PURINE DERIVATIVE AS AN ACTIVE INGREDIENT AS AN ENHANCER OF INSULIN SECRETION AND A MEDICAMENT FOR THE TREATMENT OF DIABETES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1092435-A1 | REMEDIES FOR DIABETES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-04-18 | — | — | EP | disclosed |