Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | GABRP | O00591 | 4/20 | 0.53 |
| ▸ | GABRD | O14764 | 4/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.53 |
| ▸ | GABRE | P78334 | 4/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511881 | 0.89 | NR4A2 (0.65) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28521278 | 0.89 | NR4A2 (0.58) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28511912 | 0.85 | NR4A2 (0.57) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28519317 | 0.85 | MAPT (0.60) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14554206 | 0.85 | RAB9A (0.66) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11924916 | 0.81 | GABRP (0.71) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24906134 | 0.80 | NR4A2 (0.70) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30279599 | 0.80 | NR4A2 (0.70) | NR4A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1858919 | 0.78 | NR4A2 (0.69) | NR4A2RAB9ALMNAMAPTMEN1 | |
| SCHEMBL6031174 | 0.78 | NR4A2 (0.74) | NR4A2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112294798-A | Composition for reducing absorption of lipase inhibitor in digestive tract | 中山万汉制药有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-112263575-A | Composition containing orlistat and indoxyl acetamide compound and application thereof | 中山万汉制药有限公司 | 2021-01-26 | — | — | CN | claimed |
| CN-112294798-A | Composition for reducing absorption of lipase inhibitor in digestive tract | 中山万汉制药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112263575-A | Composition containing orlistat and indoxyl acetamide compound and application thereof | 中山万汉制药有限公司 | 2021-01-26 | — | — | CN | disclosed |