Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | GABRP | O00591 | 5/20 | 0.58 |
| ▸ | GABRD | O14764 | 5/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.58 |
| ▸ | GABRE | P78334 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279599 | 1.00 | NR4A2 (0.70) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL6031174 | 0.86 | NR4A2 (0.74) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL29377618 | 0.86 | NR4A2 (0.74) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL30276803 | 0.85 | NR4A2 (0.65) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL28511881 | 0.85 | NR4A2 (0.65) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL1558974 | 0.84 | NR4A2 (0.71) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL14554206 | 0.83 | RAB9A (0.66) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL7385581 | 0.83 | LMNA (0.70) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL7382576 | 0.83 | NR4A2 (0.69) | NR4A2LMNAMEN1KMT2AMITF | |
| SCHEMBL1858919 | 0.83 | NR4A2 (0.69) | NR4A2LMNAMEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383850-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-11-21 | — | — | US | disclosed |
| WO-2023019367-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023019367-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023002005-A1 | METHOD FOR PREPARING A TRYPTAMINE DERIVATIVE. | GH Research Ireland Limited (IE) | 2023-01-26 | — | — | WO | disclosed |
| EP-4122916-A1 | METHOD FOR PREPARING AN ORGANIC COMPOUND | GH Research Ireland Limited (IE) | 2023-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383850-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | TPH1, HTR5A, TPH2 | NR4A2 2128/4885LMNA 3074/4885MEN1 1887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.