Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533558 | 0.87 | MGAM (0.45) | TSHRRAB9ANPC1HPGDKDM4E | |
| SCHEMBL28906997 | 0.84 | TSHR (0.54) | TSHRALOX15CASP1RAB9ANPC1 | |
| SCHEMBL28528353 | 0.83 | GAA (0.40) | TSHRRAB9ANPC1HPGDKDM4E | |
| SCHEMBL28526407 | 0.83 | SMN1; SMN2 (0.41) | TSHRPTPN1RAB9ANPC1HPGD | |
| SCHEMBL595453 | 0.79 | KDM4E (0.57) | RAB9ANPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL28528358 | 0.74 | RAB9A (0.49) | TSHRALOX15CASP1RAB9ANPC1 | |
| SCHEMBL28520867 | 0.74 | RAB9A (0.45) | TSHRALOX15CASP1RAB9ANPC1 | |
| SCHEMBL26745339 | 0.74 | ALOX15 (0.51) | TSHRALOX15CASP1PTPN1RAB9A | |
| SCHEMBL28710167 | 0.72 | TSHR (0.82) | TSHRALOX15CASP1PTPN1RAB9A | |
| SCHEMBL28411650 | 0.72 | TSHR (0.82) | TSHRALOX15CASP1PTPN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530438-B | Benzothiazole-oxazole alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2020-12-29 | — | — | CN | disclosed |