Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228822 | 0.87 | TSHR (0.58) | TSHRALDH1A1LMNACYP3A4TP53 | |
| SCHEMBL31228867 | 0.86 | TSHR (0.53) | TSHRALDH1A1LMNACYP3A4TP53 | |
| SCHEMBL31228741 | 0.85 | TSHR (0.55) | TSHRALDH1A1LMNACYP3A4TP53 | |
| SCHEMBL31228728 | 0.83 | TSHR (0.49) | TSHRALDH1A1LMNACYP3A4TP53 | |
| SCHEMBL31228740 | 0.83 | ALDH1A1 (0.54) | TSHRALDH1A1LMNACYP3A4TP53 | |
| SCHEMBL9009920 | 0.81 | ALDH1A1 (0.68) | TSHRALDH1A1LMNACYP3A4TP53 | |
| SCHEMBL6246723 | 0.80 | THRB (0.49) | TSHRALDH1A1LMNACYP3A4MEN1 | |
| SCHEMBL28440618 | 0.80 | MEN1 (0.64) | ALDH1A1LMNACYP3A4MEN1NR1I2 | |
| SCHEMBL29720413 | 0.80 | MEN1 (0.64) | ALDH1A1LMNACYP3A4MEN1NR1I2 | |
| SCHEMBL15613423 | 0.79 | TSHR (0.68) | TSHRALDH1A1LMNACYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384520-A | Method for producing oligonucleotide compound | 日本新药株式会社 | 2021-02-19 | — | — | CN | disclosed |