Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720413 | 1.00 | MEN1 (0.64) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL6246723 | 0.85 | THRB (0.49) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL533850 | 0.80 | CCNB2 (0.53) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL28519403 | 0.80 | TSHR (0.52) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27731656 | 0.80 | LMNA (0.66) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL12516907 | 0.80 | CNR2 (0.49) | CNR1CNR2PTPN11S1PR3ALDH1A1 | |
| SCHEMBL874312 | 0.78 | LMNA (1.00) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL4656110 | 0.78 | LMNA (1.00) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL9417650 | 0.78 | LMNA (1.00) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL5147507 | 0.78 | LMNA (1.00) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485582-B | Fluorenone-based organogel molecule and preparation method and application thereof | 南京工业大学 | 2020-07-17 | — | — | CN | disclosed |