Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198398 | 1.00 | GPR119 (0.53) | GPR119NAMPTJAK2JAK1PTPN2 | |
| SCHEMBL28519489 | 1.00 | GPR119 (0.53) | GPR119NAMPTJAK2JAK1PTPN2 | |
| SCHEMBL28527384 | 0.86 | GPR119 (0.44) | GPR119NAMPTSTS | |
| SCHEMBL23578772 | 0.82 | HRH3 (0.45) | GPR119NAMPT | |
| SCHEMBL29407322 | 0.82 | HRH3 (0.45) | GPR119NAMPT | |
| SCHEMBL30329475 | 0.82 | HRH3 (0.45) | GPR119NAMPT | |
| SCHEMBL29855712 | 0.81 | GPR119 (0.40) | GPR119STS | |
| SCHEMBL26648280 | 0.81 | GPR119 (0.40) | GPR119STS | |
| SCHEMBL24775463 | 0.78 | GPR119 (0.50) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL23579324 | 0.76 | RIPK1 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |