Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855712 | 0.86 | GPR119 (0.40) | GPR119FPR2HPGDSKDM1ASTS | |
| SCHEMBL28519489 | 0.86 | GPR119 (0.53) | GPR119STSNAMPT | |
| SCHEMBL26648280 | 0.86 | GPR119 (0.40) | GPR119FPR2HPGDSKDM1ASTS | |
| SCHEMBL28519485 | 0.86 | GPR119 (0.53) | GPR119STSNAMPT | |
| SCHEMBL31198398 | 0.86 | GPR119 (0.53) | GPR119STSNAMPT | |
| SCHEMBL23578772 | 0.85 | HRH3 (0.45) | GPR119KDM1AHRH3NAMPT | |
| SCHEMBL30329475 | 0.85 | HRH3 (0.45) | GPR119KDM1AHRH3NAMPT | |
| SCHEMBL29407322 | 0.85 | HRH3 (0.45) | GPR119KDM1AHRH3NAMPT | |
| SCHEMBL29172856 | 0.83 | RBP4 (0.39) | KDM4E | |
| SCHEMBL28524493 | 0.82 | NAMPT (0.46) | GPR119USP30HPGDSKDM4EKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |