SCHEMBL28519625

SCHEMBL28519625

COCCOOC(=O)c1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
KMT2A Q03164 6/20 0.42
MEN1 O00255 3/20 0.42
RAB9A P51151 5/20 0.42
NPC1 O15118 5/20 0.42
POLB P06746 2/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 3/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KCNK3 O14649 1/20 0.41
KCNK9 Q9NPC2 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28476894 0.95 TSHR (0.50) TSHRKMT2AMEN1RAB9ANPC1
SCHEMBL27875047 0.85 MEN1 (0.43) TSHRKMT2AMEN1RAB9ANPC1
SCHEMBL7631678 0.83 MEN1 (0.42) TSHRKMT2AMEN1RAB9ANPC1
Benzene SCHEMBL27418497 0.83 ALDH1A1 (0.51) TSHRKMT2AMEN1RAB9ANPC1
SCHEMBL14409194 0.83 TSHR (0.79) TSHRKMT2AMEN1RAB9ANPC1
SCHEMBL27460123 0.82 TSHR (0.53) TSHRHPGDALDH1A1LMNAHTT
SCHEMBL27704810 0.81 TSHR (0.46) TSHRKMT2AMEN1RAB9ANPC1
SCHEMBL15768394 0.81 TSHR (0.55) TSHRKMT2AMEN1RAB9ANPC1
SCHEMBL7627158 0.81 ADRB2 (0.42) TSHRKMT2AMEN1RAB9ANPC1
SCHEMBL27880352 0.81 TSHR (0.57) TSHRKMT2AMEN1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112322306-B Ultrahigh-polarity chiral liquid crystal material, liquid crystal laser and preparation method thereof 华南理工大学 2022-05-24 CN disclosed
CN-112375168-B Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2022-03-29 CN disclosed
CN-112375168-A Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2021-02-19 CN disclosed
CN-112342032-A Rod-like polar liquid crystal molecule, preparation method thereof and rod-like polar nematic liquid crystal 华南理工大学 2021-02-09 CN disclosed
CN-112322306-A Ultrahigh-polarity chiral liquid crystal material, liquid crystal laser and preparation method thereof 华南理工大学 2021-02-05 CN disclosed