Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528972 | 0.85 | PTGDR2 (0.43) | HTR6KDM1APDE4APDE4BPDE4C | |
| SCHEMBL5413550 | 0.82 | KDM4E (0.63) | HTR6KDM4EUBE2NL3MBTL1KLK7 | |
| SCHEMBL13257978 | 0.81 | HTR6 (0.52) | HTR6KDM1APDE4APDE4BPDE4C | |
| SCHEMBL31593169 | 0.81 | HTR6 (0.48) | HTR6KDM1APDE4APDE4BPDE4C | |
| SCHEMBL1308178 | 0.81 | HTR6 (0.48) | HTR6KDM1APDE4APDE4BPDE4C | |
| SCHEMBL3474983 | 0.77 | PDE4A (0.80) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5440583 | 0.74 | HTR6 (0.80) | HTR6KDM4EALDH1A1HTTNPSR1 | |
| SCHEMBL1307215 | 0.73 | HTR6 (0.43) | HTR6KDM1APDE4APDE4BPDE4C | |
| SCHEMBL13257975 | 0.73 | KDM4E (0.51) | HTR6KDM1AKDM4EUBE2NL3MBTL1 | |
| SCHEMBL31315863 | 0.73 | KDM1A (0.50) | HTR6KDM1AKDM4EUBE2NL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375104-A | Phospholactone indole compound and preparation method thereof | 苏州大学 | 2021-02-19 | — | — | CN | disclosed |