Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519682 | 0.85 | HTR6 (0.46) | KDM4EUBE2NHTR6L3MBTL1KLK7 | |
| SCHEMBL5413550 | 0.82 | KDM4E (0.63) | KDM4EUBE2NHTR6L3MBTL1KLK7 | |
| SCHEMBL31315845 | 0.81 | KDM4E (0.45) | PTGDR2KDM4EUBE2NHTR6L3MBTL1 | |
| SCHEMBL1889292 | 0.81 | CA1 (0.49) | PTGDR2KDM4EUBE2NHTR6L3MBTL1 | |
| SCHEMBL2134749 | 0.80 | KDM4E (0.67) | PTGDR2KDM4EUBE2NHTR6L3MBTL1 | |
| SCHEMBL2939548 | 0.75 | CA2 (0.53) | PTGDR2KDM4EUBE2NHTR6L3MBTL1 | |
| SCHEMBL2939545 | 0.75 | CA2 (0.53) | PTGDR2KDM4EUBE2NHTR6L3MBTL1 | |
| SCHEMBL28472630 | 0.75 | HTR6 (0.46) | PTGDR2HTR6PDE4APDE4BPDE4C | |
| SCHEMBL21461528 | 0.75 | L3MBTL1 (0.56) | PTGDR2HTR6L3MBTL1PDE4APDE4B | |
| SCHEMBL28471053 | 0.74 | ALK (0.75) | PTGDR2HTR6PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375104-A | Phospholactone indole compound and preparation method thereof | 苏州大学 | 2021-02-19 | — | — | CN | disclosed |