Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GRK6 | P43250 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396047 | 1.00 | KDM4E (0.38) | KDM4EGPR3PIM1HTR1ADRD2 | |
| SCHEMBL7470209 | 0.81 | KDM4E (0.42) | KDM4EGPR3PIM1HTR1ADRD2 | |
| SCHEMBL17413681 | 0.73 | KDM4E (0.43) | KDM4EGPR3ADRA2ALMNAMAPT | |
| SCHEMBL17413694 | 0.73 | KDM4E (0.43) | KDM4EGPR3ADRA2ALMNAMAPT | |
| SCHEMBL7833962 | 0.71 | KDM4E (0.47) | KDM4EGPR3PIM1HTR1ADRD2 | |
| SCHEMBL159416 | 0.68 | KDM4E (0.59) | KDM4EGPR3LMNAMAPTNPC1 | |
| SCHEMBL31684807 | 0.68 | KDM4E (0.59) | KDM4EGPR3LMNAMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL9110426 | 0.66 | KDM4E (0.57) | KDM4EGPR3LMNAMAPTNPC1 | |
| SCHEMBL12799615 | 0.66 | HSD17B10 (0.39) | KDM4EPOLB | |
| SCHEMBL22653576 | 0.64 | KDM4E (0.50) | KDM4EGPR3LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116999571-A | Antibody-drug conjugates comprising anti-B7-H3 antibodies | 尹图赛利有限公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-4171655-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING ANTI-B7-H3 ANTIBODIES | Intocell, Inc. (KR) | 2023-05-03 | — | — | EP | disclosed |
| CN-115942978-A | Antibody-drug conjugates comprising anti-B7-H3 antibodies | 尹图赛利有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113444111-A | Novel benzodiazepine derivative and use thereof | 尹图赛利有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112166115-A | Novel benzodiazepine derivatives and uses thereof | 尹图赛利有限公司 | 2021-01-01 | — | — | CN | disclosed |